To meet the requirements of Remote Medical Information System (RMIS) application, a proposal about how to design and develop Android applications in RMIS combined with the characteristic of Android system was proposed. Firstly, the framework of RMIS and the architecture of Android Operating System (OS) were introduced, and then the development method of serial port, bluetooth, socket, HTTP and other means of communication and the application of these technologies in medical data acquisition and mobile data processing were analyzed, the Representational State Transfer (REST) Web service’s realization was introduced as well. Finally, data acquisition application and mobile information management application based on Android were carried out. The results show that Android can be used in RMIS in many aspects.